Intermediate-scale for clinical & commercial production
The scale-X™ carbo system is a GMP-compatible solution for process development, clinical and commercial production. It features a structured-fixed bed bioreactor and in-line TFF concentration automated through a centralized interface. This intermediate-scale enables to bridge the gap between R&D and commercial production offering high productivity in a low footprint with scalable processing.
Applications
Viral vectors
Viral vaccines
Oncolytic viruses
Exosomes
Adherent cells
Suspension cells
Reinventing benchtop production
The scale-X carbo system is a bench-scale automated cell culture system for expression and concentration of viral drug substance. It features a single-use bioreactor offering 10 to 30 m² surface for cell growth.
The scale-X™ carbo system is suited for rapid process development and cost-effective clinical production.
FEATURES
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A unique solution for rapid process development
Benefits
High capacity in low footprint
Through intensified virus production integrated with in-line product concentration.
Intermediate-scale system
Different applications are possible with bioreactors for both R&D and GMP production.
Scalability
Linear scalability between the scale-X carbo bioreactors (10m² and 30m²) and scale-X nitro bioreactors (200m² and 600m²).
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Related Publications
scale-X™ carbo bioreactor system for rapid process development
The scale-X™ carbo system is a bench-scale automated cell culture system for expression and concentration of viral drug substance, suited for rapid process development and cost-effective clinical production.
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Promising Vero cell growth in scale-X™ bioreactors
Case study comparing adherent Vero cell growth on microcarriers and intensified, fixed-bed scale-X bioreactors hydro (2.4 m²) and carbo (10-30 m²). Results demonstrate the scale-X bioreactors as a suitable alternative to traditional technologies.
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Successful process transfer of vaccine candidates in scale-X™ hydro bioreactor
Direct process reproduction from multi-layer bioreactor and roller bottles for four vaccine antigens using three different cell lines (CEF, WI-38 and Vero cells)
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Shortcut to your success
Our experienced Bioprocess & Field Services team is available to support you to quickly and efficiently start your development activities. From the installation of the equipment to process training and maintenance, they are committed to provide the support you need.