Engineering characterization series: Scalable process design
Mastering scalable process design with the scale-X™ Technology
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Engineering characterization series: Gas exchange
Read more about the potential of next-generation gas exchange technology.
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Engineering characterization series: mixing
Discover how the scale-X™ platform combines theoretical rigor and cutting-edge technology to redefine the standards of bioreactor design.
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Engineering characterization series: the basic design principles of the scale-X™ technology
Explore how scale-X™ bioreactors overcome bioprocessing challenges and improve scalability in bioproduction.
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Tiny but Mighty – Sophisticated Innovation for Early-Stage Research
The 0.5 m² scale-X™ nexo bioreactor redefines what’s possible in early-stage research – delivering premium sophistication in a compact design.
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Unlock new levels of insight, efficiency, and confidence in your process with the Skaia™ vision platform
This innovative approach estimates cell number inside your scale-X™ bioreactor without the need for direct cell sampling, ensuring optimal productivity and efficiency in your workflow.
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Intensified extracellular vesicle production in fixed-bed bioreactors
Discover low-footprint, automated solutions for low-cost extracellular vesicles manufacturing
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Expansion and harvest of fish stem cells using the scale-X™ bioreactor
A promising alternative for scaled up production of cultivated fish
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Maximizing cost-efficiency, reducing GMP footprint and eliminating bottlenecks in lentiviral virus production: A Case Study with the Cytegrity™ Producer Cell Line in the scale-X™ Fixed-Bed Bioreactor
Tackle the challenges in GMP Lentiviral virus production processes
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Production of lentiviral vector for CAR-T cell therapy development
A process transfer of lentiviral vector production with adherent HEK293T cells from a conventional system to a novel fixed-bed bioreactor
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Seed train or seed culture expansion process
Wondering what it would mean to intensify your seed expansion process using the scale-X cell collect module?
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Addressing scale-up challenges through technological innovation for cost-effective vaccine development
Deep dive into scaling viral manufacturing cost-effectively
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Redefining extracellular vesicle production: proof of concept study evaluating structured fixed-bed bioreactor for high-capacity production
Discover how Univercells Technologies’ scale-X™ fixed-bed bioreactors achieved 2-fold increase in EV productivity enabling scalable production from proof-of-concept to large-scale continuous manufacturing
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Advantages of optimized AAV harvest in fixed-bed bioreactors
The process optimization for AAV harvest contributes to high product recovery, small volumes, reduced host cell impurities and increased full/empty capsid ratio to address time and capacity gaps.
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hMSC-derived extracellular vesicles production in the scale-X™ hydro fixed-bed bioreactor
Proof-of-concept of exosomes manufacturing in scale-X™ bioreactor to demonstrate advantages of intensified and integrated platforms
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From tech transfer to commercial scale viral manufacturing in 8 months – a CDMO case study
Innovative, scalable-by-design fixed-bed technology addresses limitations associated with stirred-tank bioreactors – Tech transfer study by CDMO Exothera
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Linear and predictable scale-up in the fixed-bed bioreactor
The scale-X™ bioreactors’ design and performance features allow for linear predictability for process parameter scale-up
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Improving development troubleshooting
Achieve your goal in biological processes by improving development troubleshooting, focusing on root cause analysis.
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AAV manufacturing: The benefits of growing serum-free, suspension HEK293 cells in the scale-X™ fixed-bed bioreactor
Achieve 3-fold increase in AAV-2 cell-specific productivity using a suspension HEK293F cell line in the scale-X™ structured fixed-bed bioreactor
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Lentivirus production study in the scale-X™ fixed-bed bioreactor
Implementation of a metabolite-based cell density estimation and evaluation of harvest strategies for Lentivirus production with HEK293T cells
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AAV manufacturing: The benefits of growing serum-free, suspension HEK293 cells in the scale-X fixed-bed bioreactor
Meet capacity challenges growing a suspension HEK293 cell line in serum-free conditions to produce an AAV-2 product in high quantities with a scale-X™ fixed-bed bioreactor
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Key considerations when using recirculation and perfusion processes in the scale-X™ fixed-bed bioreactor
Recirculation and perfusion are two advantageous methods for supplying medium nutrients to the cells in the scale-X™ structured fixed-bed bioreactor and for harvesting the cell-mediated product.
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Addressing large scale inoculation bottlenecks by intensifying and automating the seed train
Case study for HEK293 cell harvest from fixed-bed fibers
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A proven solution to tackle gene therapy manufacturing challenges
The role of intensification and integration in rapid deployment of large viral production capacity
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Simplifying seed train: a benchtop system for intensified inoculation of large-scale bioreactors
Streamlined bioreactor-to-bioreactor seed train
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How to find success with lentiviral production using fixed-bed bioreactor technology?
Highly productive lentivirus manufacture using the scale-X™ technology
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Intensified and integrated biomanufacturing technologies
Scalable and high-productivity manufacture of advanced therapies
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Scalable seed train intensification and automation for adherent cell cultures with the scale-X™ bioreactor
Achievement of large-scale, cost-efficient enzymatic cell collection from structured fixed-bed bioreactors to facilitate and de-risk seed train generation
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Reaching high capacity without large-scale bioreactors
Redefining the concepts of scale and flexibility
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A Rapid Fixed-Bed Proof-of-Concept Bioreactor
Static cell cultivation and production process transferred to the scale-X™ hydro bioreactor.
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