scale-X™ nexo system

Tiny but Mighty: Sophisticated innovation for early-stage research

The 0.5 m² scale-X™ nexo bioreactor redefines what’s possible in early-stage research – delivering premium sophistication in a compact design. Its scalable platform seamlessly supports direct scale-up to 600 m² with minimal adaptations, ensuring a smooth, accelerated, and low-risk process from small to large-scale production.

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A solution for early process development

Simple fluid management
Easy consumables set-up
High cell density culture and production
In-line monitoring and automated process control

Take your scale-X nexo system
to the next level

Compatible with the Skaia™ vision software for advanced cell monitoring and prediction, the scale-X nexo bioreactor delivers unmatched performance for fast, reliable, and scalable bioprocessing.

Benefits

Reduce costs per run by up to 60%1

Meticulously engineered for optimized performance in a compact design, the scale-X nexo system maximizes efficiency by minimizing resource use. Reach cost-effective bioprocess development with our low-volume, low-surface fixed-bed bioreactor.

Specifically designed for early-stage screening and research, it reduces the need for media, reagents, and seed-train efforts, significantly lowering your cost per run1 and resource requirements.

Accelerate your path to market with seamless scalability

Scale up your bioprocess effortlessly with our bioreactor, designed for direct scalability. With minimal process adaptation required, achieve consistency in cell distribution and high cell density across scales, ensuring reliable results. Be first to market by shortening your development timeline with direct scalability to the benchtop scale-X carbo bioreactor (10-30 m²) and the NevoLine™ Upstream platform for commercial-scale manufacturing (200-600 m²).

Elevate your workflow with cutting-edge components

Boost productivity with the advanced and structured design of the scale-X nexo fixed-bed bioreactor, ensuring optimal cell growth for maximum efficiency. Gamma-irradiated, single-use components eliminate preparation time while minimizing contamination risk. The dismantlable design enables easy retrieval of the fixed-bed for accurate cell counting, laying the basis for smooth and reliable scale-up. With a flexible manifold, the scale-X nexo bioreactor adapts easily to diverse applications, delivering premium, tailored performance.

Key applications

Viral vectors for cell and gene therapy

Viral vaccines (human & veterinary)

Oncolytic viruses

Exosomes

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Related Publications


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scale-X™ nexo system?

  1. Based on Univercells Technologies’ internal data comparing the scale-X nexo bioreactor system to entry-level fixed-bed bioreactors from competitors. The reported savings of up to 60% may vary depending on specific process conditions, bioreactor configurations, and operational practices. Actual results will depend on the user’s workflow and setup. ↩︎
  2. Based on Univercells Technologies’ internal data comparing the scale-X nexo bioreactor system to entry-level fixed-bed bioreactors from competitors. The reported savings of up to 60% may vary depending on specific process conditions, bioreactor configurations, and operational practices. Actual results will depend on the user’s workflow and setup. ↩︎

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