Engineering characterization series: Gas exchange

Gas exchange in scale-X fixed-bed bioreactors

Maintaining optimal gas exchange is vital for the success of mammalian cell cultures in biopharmaceutical production. Unlike the natural physiological environment, where oxygen supply and carbon dioxide removal are finely regulated by the organism’s respiratory system, in-vitro systems rely on advanced engineering to replicate these processes.

Chapter 3 of our Engineering Characterization Series delves into the critical principles and practical implementation of gas exchange within the scale-X technology. Discover how innovative design ensures optimal oxygen delivery and carbon dioxide removal to mimic physiological conditions, supporting robust cell growth and productivity. Whether you’re optimizing bioreactor performance or scaling up production, this chapter offers actionable insights and cutting-edge solutions for enhancing your cell culture processes.

Interested?

Download the paper and read more about the potential of next-generation gas exchange technology.

Download the third engineering characterization article

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